EC 2 - Transferases
EC 2.7 - Transferring phosphorus-containing groups
EC 2.7.1 - Phosphotransferases with an alcohol group as acceptor
EC 2.7.1.49 - Hydroxymethylpyrimidine kinase
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ENZYME view
IntEnz Enzyme Nomenclature
EC 2.7.1.49
Names
Accepted name:
hydroxymethylpyrimidine kinase
Other
name:
hydroxymethylpyrimidine kinase (phosphorylating)
Systematic name:
ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase
Reaction
- ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine = ADP + 4-amino-2-methyl-5-(phosphomethyl)pyrimidine
Comments:
CTP, UTP and GTP can act as donors.
Links to other databases
Gene Ontology:
GO:0008902
CAS Registry Number:
9026-55-5
References
-
The biosynthesis of thiamine. III. Mechanism of enzymatic formation of the pyrophosphate ester of 2-methyl-4-amino-5-hydroxymethylpyrimidine.J. Biol. Chem. 236 : 2768-2771 (1961).
[EC 2.7.1.49 created 1965]