IntEnz - EC 2.7.1.39

EC 2 - Transferases

EC 2.7 - Transferring phosphorus-containing groups

EC 2.7.1 - Phosphotransferases with an alcohol group as acceptor

EC 2.7.1.39 - Homoserine kinase

IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.7.1.39

Names

Accepted name:

homoserine kinase

Other names:

HSK
homoserine kinase (phosphorylating)

Systematic name:

ATP:L-homoserine O-phosphotransferase

Reaction

13985 [IUBMB]

ATP

ATP

Name origin: UniProt - CHECKED (C)

CHEBI:30616

Formula: C10H12N5O13P3
Charge: -4

ChEBI compound status: CHECKED (C)

+

L-homoserine

L-homoserine

Name origin: UniProt - CHECKED (C)

CHEBI:57476

Formula: C4H9NO3
Charge: 0

ChEBI compound status: CHECKED (C)

=

ADP

ADP

Name origin: UniProt - CHECKED (C)

CHEBI:456216

Formula: C10H12N5O10P2
Charge: -3

ChEBI compound status: CHECKED (C)

+

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

O-phospho-L-homoserine

O-phospho-L-homoserine

Name origin: UniProt - CHECKED (C)

CHEBI:57590

Formula: C4H8NO6P
Charge: -2

ChEBI compound status: CHECKED (C)

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Protein domains and families: PROSITE:PDOC00545

Structural data: CSA , EC2PDB

Gene Ontology: GO:0004413

CAS Registry Number: 9026-58-8

UniProtKB/Swiss-Prot: (439) [show] [UniProt]

References

Flavin, M. and Slaughter, C.

Purification and properties of threonine synthetase of Neurospora.

J. Biol. Chem. 235: 1103-1108 (1960).
Watanabe, Y., Konishi, S. and Shimura, K.

Biosynthesis of threonine from homoserine. VI. Homoserine kinase.

J. Biochem. (Tokyo) 44: 299-307 (1957).

[EC 2.7.1.39 created 1961]