EC 2.7.1.177 - L-threonine kinase

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IntEnz Enzyme Nomenclature
EC 2.7.1.177

Names

Accepted name:
L-threonine kinase
Other name:
PduX
Systematic name:
ATP:L-threonine O3-phosphotransferase

Reaction

Comments:

The enzyme is involved in the de novo synthesis of adenosylcobalamin. It is specific for ATP and free L-threonine. In the bacterium Salmonella enterica the activity with CTP, GTP, or UTP is 6, 11, and 3% of the activity with ATP.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Fan, C., Bobik, T. A.
    The PduX enzyme of Salmonella enterica is an L-threonine kinase used for coenzyme B12 synthesis.
    J. Biol. Chem. 283: 11322-11329 (2008). [PMID: 18308727]
  2. Fan, C., Fromm, H. J., Bobik, T. A.
    Kinetic and functional analysis of L-threonine kinase, the PduX enzyme of Salmonella enterica.
    J. Biol. Chem. 284: 20240-20248 (2009). [PMID: 19509296]

[EC 2.7.1.177 created 2012]