EC 2.7.1.143 - Diphosphate-purine nucleoside kinase

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IntEnz Enzyme Nomenclature
EC 2.7.1.143

Names

Accepted name:
diphosphate-purine nucleoside kinase
Other name:
pyrophosphate-purine nucleoside kinase
Systematic name:
diphosphate:purine nucleoside phosphotransferase

Reaction

Comments:

The enzyme from the Acholeplasma class of Mollicutes catalyses the conversion of adenosine, guanosine and inosine to AMP, GMP and IMP. ATP cannot substitute for diphosphate as a substrate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008842
CAS Registry Number: 70356-41-1

References

  1. Tryon, V.V., Pollack, D.
    Purine metabolism in Acholeplasma laidlawii B: novel PPi-dependent nucleoside kinase activity.
    J. Bacteriol. 159: 265-270 (1984). [PMID: 6330034]
  2. Tryon, V.V., Pollack, J.D.
    Distinctions in Mollicutes purine metabolism: pyrophosphate-dependent nucleoside kinase and dependence on guanylate salvage.
    Int. J. Systematic Bacteriol. 35: 497-501 (1985).

[EC 2.7.1.143 created 1999]