EC - L-tryptophan—pyruvate aminotransferase

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IntEnz Enzyme Nomenclature


Accepted name:
L-tryptophan—pyruvate aminotransferase
Other names:
TAA1 (gene name)
vt2 (gene name)
Systematic name:
L-tryptophan:pyruvate aminotransferase



This plant enzyme, along with EC, indole-3-pyruvate monooxygenase, is responsible for the biosynthesis of the plant hormone indole-3-acetate from L-tryptophan.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Tao, Y., Ferrer, J. L., Ljung, K., Pojer, F., Hong, F., Long, J. A., Li, L., Moreno, J. E., Bowman, M. E., Ivans, L. J., Cheng, Y., Lim, J., Zhao, Y., Ballare, C. L., Sandberg, G., Noel, J. P., Chory, J.
    Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants.
    Cell 133 : 164-176 (2008). [PMID: 18394996]
  2. Mashiguchi, K., Tanaka, K., Sakai, T., Sugawara, S., Kawaide, H., Natsume, M., Hanada, A., Yaeno, T., Shirasu, K., Yao, H., McSteen, P., Zhao, Y., Hayashi, K., Kamiya, Y., Kasahara, H.
    The main auxin biosynthesis pathway in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A. 108 : 18512-18517 (2011). [PMID: 22025724]
  3. Phillips, K. A., Skirpan, A. L., Liu, X., Christensen, A., Slewinski, T. L., Hudson, C., Barazesh, S., Cohen, J. D., Malcomber, S., McSteen, P.
    vanishing tassel2 encodes a grass-specific tryptophan aminotransferase required for vegetative and reproductive development in maize.
    Plant Cell 23 : 550-566 (2011). [PMID: 21335375]
  4. Zhao, Y.
    Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants.
    Mol Plant 5 : 334-338 (2012). [PMID: 22155950]

[EC created 2012]