EC 2.6.1.44 - Alanine—glyoxylate transaminase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 2.6.1.44
Names
Accepted name:
alanine—glyoxylate transaminase
Other
names:
L-alanine—glycine transaminase
AGT
alanine—glyoxylate aminotransferase
alanine—glyoxylic aminotransferase
AGT
alanine—glyoxylate aminotransferase
alanine—glyoxylic aminotransferase
Systematic name:
L-alanine:glyoxylate aminotransferase
Reaction
- L-alanine + glyoxylate = pyruvate + glycine
Cofactor
Comments:
A pyridoxal-phosphate protein. With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. A second component also catalyses the reaction of EC 2.6.1.51 serine-pyruvate transaminase.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
DIAGRAM
,
DIAGRAM
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Protein domains and families:
PROSITE:PDOC00514
Gene Ontology:
GO:0008453
CAS Registry Number:
9015-67-2
References
-
Characteristics of hepatic alanine-glyoxylate aminotransferase in different mammalian species.Biochem. J. 169 : 113-122 (1978). [PMID: 629740]
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Co-purification of alanine-glyoxylate aminotransferase with 2-aminobutyrate aminotransferase in rat kidney.Biochim. Biophys. Acta 715 : 97-104 (1982). [PMID: 6803844]
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Isolation and characterization of an L-alanine: glyoxylate aminotransferase from human liver. J.Biol. Chem. 242 : 3614-3619 (1967). [PMID: 6038488]
[EC 2.6.1.44 created 1972, modified 1982]