EC 2.6.1.42 - Branched-chain-amino-acid transaminase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 2.6.1.42
Names
Accepted name:
branched-chain-amino-acid transaminase
Other
names:
L-branched chain amino acid aminotransferase
branched-chain amino acid aminotransferase
branched-chain amino acid—glutamate transaminase
branched-chain aminotransferase
glutamate—branched-chain amino acid transaminase
transaminase B
branched-chain amino acid aminotransferase
branched-chain amino acid—glutamate transaminase
branched-chain aminotransferase
glutamate—branched-chain amino acid transaminase
transaminase B
Systematic name:
branched-chain-amino-acid:2-oxoglutarate aminotransferase
Reaction
- L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate
Cofactor
Comments:
Also acts on L-isoleucine and L-valine. Different from EC 2.6.1.66 valine-pyruvate transaminase.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
DIAGRAM
,
DIAGRAM
,
DIAGRAM
,
DIAGRAM
,
DIAGRAM
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Protein domains and families:
PROSITE:PDOC00618
CAS Registry Number:
9054-65-3
References
-
Transaminases of branched chain amino acids. IV. Purification and properties of two enzymes from rat liver.Biochim. Biophys. Acta 159 : 276-284 (1968). [PMID: 4968655]
-
Transaminase of branched chain amino acids. VI. Purification and properties of the hog brain enzyme.J. Biochem. (Tokyo) 65 : 539-544 (1969). [PMID: 4979711]
-
Transaminase of branched chain amino acids. I. Branched chain amino acids-α-ketoglutarate transaminase.J. Biochem. (Tokyo) 59 : 160-169 (1966). [PMID: 5943594]
-
Leucine aminotransferase. II. Purification and characterization.J. Biol. Chem. 241 : 4396-4405 (1966). [PMID: 5922965]
-
Transamination in Escherichia coli.J. Biol. Chem. 200 : 591-604 (1953). [PMID: 13034817]
[EC 2.6.1.42 created 1972]