EC 2.6.1.37 - 2-aminoethylphosphonate—pyruvate transaminase

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IntEnz Enzyme Nomenclature
EC 2.6.1.37

Names

Accepted name:
2-aminoethylphosphonate—pyruvate transaminase
Other names:
(2-aminoethyl)phosphonate aminotransferase
(2-aminoethyl)phosphonate transaminase
(2-aminoethyl)phosphonic acid aminotransferase
2-aminoethylphosphonate aminotransferase
2-aminoethylphosphonate—pyruvate aminotransferase
Systematic name:
(2-aminoethyl)phosphonate:pyruvate aminotransferase

Reaction

Cofactor

Comments:

A pyridoxal-phosphate protein. 2-Aminoethylarsonate can replace 2-aminoethylphosphonate as a substrate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047304
CAS Registry Number: 37277-91-1
UniProtKB/Swiss-Prot: (81) [show] [UniProt]

References

  1. La Nauze, J.M. and Rosenberg, H.
    The identification of 2-phosphonoacetaldehyde as an intermediate in the degradation of 2-aminoethylphosphonate by Bacillus cereus.
    Biochim. Biophys. Acta 165: 438-447 (1968). [PMID: 4982500]
  2. Dumora, C., Lacoste, A.-M. and Cassaigne, A.
    Purification and properties of 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa.
    Eur. J. Biochem. 133: 119-125 (1983). [PMID: 6406228]
  3. Lacoste, A.-M., Dumora, C., Balas, L., Hammerschmidt, F. and Vercauteren, J.
    Stereochemistry of the reaction catalysed by 2-aminoethylphosphonate aminotransferase. A 1H-NMR study.
    Eur. J. Biochem. 215: 841-844 (1993). [PMID: 8394813]
  4. Lacoste, A.-M., Dumora, C., Ali, B.R.S., Neuzil, E. and Dixon, H.B.F.
    Utilization of 2-aminoethylarsonic acid in Pseudomonas aeruginosa.
    J. Gen. Microbiol. 138: 1283-1287 (1992). [PMID: 1527499]

[EC 2.6.1.37 created 1972, modified 1982, modified 2001]