EC 2.6.1.27 - Tryptophan transaminase

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IntEnz Enzyme Nomenclature
EC 2.6.1.27

Names

Accepted name:
tryptophan transaminase
Other names:
5-hydroxytryptophan-ketoglutaric transaminase
L-phenylalanine-2-oxoglutarate aminotransferase
L-tryptophan aminotransferase
L-tryptophan transaminase
hydroxytryptophan aminotransferase
tryptophan aminotransferase
Systematic name:
L-tryptophan:2-oxoglutarate aminotransferase

Reaction

Cofactor

Comments:

A pyridoxal-phosphate protein. Also acts on 5-hydroxytryptophan and, to a lesser extent, on the phenyl amino acids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050362
CAS Registry Number: 9022-98-4
UniProtKB/Swiss-Prot:

References

  1. George, H. and Gabay, S.
    Brain aromatic aminotransferase. I. Purification and some properties of pig brain L-phenylalanine-2-oxoglutarate aminotransferase.
    Biochim. Biophys. Acta 167: 555-566 (1968). [PMID: 5722279]
  2. O'Neil, S.R. and DeMoss, R.D.
    Tryptophan transaminase from Clostridium sporogenes.
    Arch. Biochem. Biophys. 127: 361-368 (1968). [PMID: 5697992]
  3. Tangen, O., Fonnum, F. and Haavaldsen, R.
    Separation and purification of aromatic amino acid transaminases from rat brain.
    Biochim. Biophys. Acta 96: 82-90 (1965). [PMID: 4285270]

[EC 2.6.1.27 created 1972]