EC - (S)-3-amino-2-methylpropionate transaminase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
(S)-3-amino-2-methylpropionate transaminase
Other names:
β-aminobutyric transaminase
L-3-aminoisobutyrate transaminase
L-3-aminoisobutyric aminotransferase
Systematic name:
(S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase



Also acts on β-alanine and other ω-amino acids having carbon chains between 2 and 5. The two enantiomers of the 2-methyl-3-oxopropionate formed by the enzyme interconvert by enolization, so that this enzyme, together with EC, (R)-3-amino-2-methylpropionate—pyruvate transaminase, provide a route for interconversion of the enantiomers of 3-amino-2-methylpropionate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047298
CAS Registry Number: 9031-95-2
UniProtKB/Swiss-Prot: (11) [show] [UniProt]


  1. Kakimoto, Y., Kanazawa, A., Taniguchi, K. and Sano, I.
    β-Aminoisobutyrate-α-ketoglutarate transaminase in relation to β-aminoisobutyric aciduria.
    Biochim. Biophys. Acta 156: 374-380 (1968). [PMID: 5641913]
  2. Tamaki, N., Sakata, S.F. and Matsuda, K.
    Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver.
    Methods Enzymol. 324: 376-389 (2000). [PMID: 10989446]

[EC created 1972, modified 1982, modified 2004]