EC 18.104.22.168 - trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific]
IntEnz Enzyme Nomenclature
- (2Z,6E)-farnesyl diphosphate + n isopentenyl diphosphate = n diphosphate + trans,polycis-polyprenyl diphosphate (n = 9-11)
Highest activity with (2Z,6E)-farnesyl diphosphate as allylic substrate. Broad product specificity with the major product being dodecaprenyl diphosphate. Synthesizes even C70 prenyl diphosphate as the maximum chain-length product .
Links to other databases
Cloning and functional analysis of cis-prenyltransferase from Thermobifida fusca.J. Biosci. Bioeng. 107 : 620-622 (2009). [PMID: 19447338]
[EC 22.214.171.124 created 2010]