EC 2.5.1.88 - trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific]

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IntEnz Enzyme Nomenclature
EC 2.5.1.88

Names

Accepted name:
trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific]
Systematic name:
(2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 9-11 isopentenyl units)

Reactions

Comments:

Highest activity with (2Z,6E)-farnesyl diphosphate as allylic substrate. Broad product specificity with the major product being dodecaprenyl diphosphate. Synthesizes even C70 prenyl diphosphate as the maximum chain-length product [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Ambo, T., Noike, M., Kurokawa, H., Koyama, T.
    Cloning and functional analysis of cis-prenyltransferase from Thermobifida fusca.
    J. Biosci. Bioeng. 107: 620-622 (2009). [PMID: 19447338]

[EC 2.5.1.88 created 2010]