EC 2.5.1.70 - Naringenin 8-dimethylallyltransferase

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IntEnz Enzyme Nomenclature
EC 2.5.1.70

Names

Accepted name:
naringenin 8-dimethylallyltransferase
Other name:
N8DT
Systematic name:
dimethylallyl-diphosphate:naringenin 8-dimethylallyltransferase

Reaction

Cofactor

Comments:

Requires Mg2+. This membrane-bound protein is located in the plastids [2]. In addition to naringenin, the enzyme can prenylate several other flavanones at the C-8 position, but more slowly. Along with EC 1.14.13.103 (8-dimethylallylnaringenin 2'-hydroxylase) and EC 2.5.1.71 (leachianone G 2''-dimethylallyltransferase), this enzyme forms part of the sophoraflavanone-G-biosynthesis pathway.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Yamamoto, H., Senda, M. and Inoue, K.
    Flavanone 8-dimethylallyltransferase in Sophora flavescens cell suspension cultures.
    Phytochemistry 54 : 649-655 (2000). [PMID: 10975499]
  2. Zhao, P., Inoue, K., Kouno, I. and Yamamoto, H.
    Characterization of leachianone G 2''-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures.
    Plant Physiol. 133 : 1306-1313 (2003). [PMID: 14551337]

[EC 2.5.1.70 created 2007]