EC 2.5.1.65 - O-phosphoserine sulfhydrylase

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IntEnz Enzyme Nomenclature
EC 2.5.1.65

Names

Accepted name:
O-phosphoserine sulfhydrylase
Other name:
O-phosphoserine(thiol)-lyase
Systematic name:
O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase

Reaction

Cofactor

Comments:

A pyridoxal-phosphate protein. The enzyme from Aeropyrum pernix acts on both O-phospho-L-serine and O3-acetyl-L-serine, in contrast with EC 2.5.1.47, cysteine synthase, which acts only on O3-acetyl-L-serine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033847
UniProtKB/Swiss-Prot:

References

  1. Mino, K. and Ishikawa, K.
    A novel O-phospho-L-serine sulfhydrylation reaction catalyzed by O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
    FEBS Lett. 551: 133-138 (2003). [PMID: 12965218]
  2. Mino, K. and Ishikawa, K.
    Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
    J. Bacteriol. 185: 2277-2284 (2003). [PMID: 12644499]
  3. Mino, K., Oda, Y., Ataka, M. and Ishikawa, K.
    Crystallization and preliminary X-ray diffraction analysis of O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
    Acta Crystallogr. D Biol. Crystallogr. 59: 338-340 (2003). [PMID: 12554945]

[EC 2.5.1.65 created 2004]