EC 2.5.1.55 - 3-deoxy-8-phosphooctulonate synthase

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IntEnz Enzyme Nomenclature
EC 2.5.1.55

Names

Accepted name:
3-deoxy-8-phosphooctulonate synthase
Other names:
2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating)
2-dehydro-3-deoxy-phosphooctonate aldolase
2-keto-3-deoxy-8-phosphooctonic synthetase
3-deoxy-D-manno-octulosonate-8-phosphate synthase
3-deoxy-D-mannooctulosonate-8-phosphate synthetase
3-deoxyoctulosonic 8-phosphate synthetase
KDOP synthase
phospho-2-keto-3-deoxyoctonate aldolase
Systematic name:
phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)

Reaction

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008676
CAS Registry Number: 9026-96-4
UniProtKB/Swiss-Prot: (323) [show] [UniProt]

References

  1. Levin, D.H. and Racker, E.
    Condensation of arabinose 5-phosphate and phosphorylenol pyruvate by 2-keto-3-deoxy-8-phosphooctonic acid synthetase.
    J. Biol. Chem. 234 : 2532-2539 (1959).
  2. Krosky, D.J., Alm, R., Berg, M., Carmel, G., Tummino, P.J., Xu, B. and Yang, W.
    Helicobacter pylori 3-deoxy-D-manno-octulosonate-8-phosphate (KDO-8-P) synthase is a zinc-metalloenzyme.
    Biochim. Biophys. Acta 1594 : 297-306 (2002). [PMID: 11904225]
  3. Asojo, O., Friedman, J., Adir, N., Belakhov, V., Shoham, Y. and Baasov, T.
    Crystal structures of KDOP synthase in its binary complexes with the substrate phosphoenolpyruvate and with a mechanism-based inhibitor.
    Biochemistry 40 : 6326-6334 (2001). [PMID: 11371194]

[EC 2.5.1.55 created 1965 as EC 4.1.2.16, transferred 2002 to EC 2.5.1.55]