EC - Uracilylalanine synthase

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IntEnz Enzyme Nomenclature


Accepted name:
uracilylalanine synthase
Other names:
O3-acetyl-L-serine acetate-lyase (adding uracil)
isowillardiine synthase
willardiine synthase
3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase
O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase
Systematic name:
O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase



Both L-willardiine and L-isowillardiine are produced in the reaction. Not identical with EC, cysteine synthase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050471
CAS Registry Number: 113573-73-2


  1. Ahmmad, M.A.S., Maskall, C.S. and Brown, E.G.
    Partial-purification and properties of willardiine and synthase activity from Pisum sativum.
    Phytochemistry 23 : 265-270 (1984).
  2. Ikegami, F., Kaneko, M., Lambein, F., Kuo, Y.-H. and Murakoshi, I.
    Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum.
    Phytochemistry 26 : 2699-2704 (1987).
  3. Murakoshi, I., Ikegami, F., Ookawa, N., Ariki, T., Haginiwa, J., Kuo, Y.-H. and Lambein, F.
    Biosynthesis of the uracilylalanines willardiine and isowillardiine in higher plants.
    Phytochemistry 17 : 1571-1576 (1978).

[EC created 1990 as EC, transferred 2002 to EC]