EC 2 - Transferases
EC 2.5 - Transferring alkyl or aryl groups, other than methyl groups
EC 2.5.1 - Transferring alkyl or aryl groups, other than methyl groups
EC 2.5.1.29 - Geranylgeranyl diphosphate synthase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 2.5.1.29
Names
Accepted name:
geranylgeranyl diphosphate synthase
Other
names:
farnesyltransferase
geranylgeranyl pyrophosphate synthase
geranylgeranyl pyrophosphate synthetase
geranylgeranyl-PP synthetase
geranylgeranyl-diphosphate synthase
farnesyltranstransferase [obsolete]
geranylgeranyl pyrophosphate synthase
geranylgeranyl pyrophosphate synthetase
geranylgeranyl-PP synthetase
geranylgeranyl-diphosphate synthase
farnesyltranstransferase [obsolete]
Systematic name:
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase
Reaction
- (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate
Comments:
Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
DIAGRAM
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Protein domains and families:
PROSITE:PDOC00407
Gene Ontology:
GO:0004311
CAS Registry Number:
9032-58-0
References
-
Occurrence and unusual properties of geranylgeranyl pyrophosphate synthetase of pig liver.Biochem. Int. 3 : 669-675 (1981).
[EC 2.5.1.29 created 1984, modifed 2011]