EC - Adenylate dimethylallyltransferase (AMP-dependent)

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IntEnz Enzyme Nomenclature


Accepted name:
adenylate dimethylallyltransferase (AMP-dependent)
Other names:
2-isopentenyl-diphosphate:AMP Δ2-isopentenyltransferase
adenylate isopentenyltransferase [ambiguous]
cytokinin synthase [ambiguous]
isopentenyltransferase [ambiguous]
Systematic name:
prenyl-diphosphate:AMP prenyltransferase



Involved in the biosynthesis of cytokinins in plants. Some isoforms from the plant Arabidopsis thaliana are specific for AMP while others also have the activity of EC, adenylate dimethylallyltransferase (ADP/ATP-dependent).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0009824
CAS Registry Number: 72840-95-0
UniProtKB/Swiss-Prot: (18) [show] [UniProt]


  1. Chen, C.-M. and Melitz, D.K.
    Cytokinin biosynthesis in a cell-free system from cytokinin-autotrophic tobacco tissue cultures.
    FEBS Lett. 107 : 15-20 (1979). [PMID: 499537]
  2. Takei, K., Sakakibara, H., Sugiyama, T.
    Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana.
    J. Biol. Chem. 276 : 26405-26410 (2001). [PMID: 11313355]
  3. Sakano, Y., Okada, Y., Matsunaga, A., Suwama, T., Kaneko, T., Ito, K., Noguchi, H., Abe, I.
    Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.).
    Phytochemistry 65 : 2439-2446 (2004). [PMID: 15381407]

[EC created 1984, modified 2002, modified 2013]