EC - sym-norspermidine synthase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
sym-norspermidine synthase
Systematic name:
S-adenosyl 3-(methylsulfanyl)propylamine:propane-1,3-diamine 3-aminopropyltransferase



The enzyme has been originally characterized from the protist Euglena gracilis [1,2]. The enzyme from the archaeon Sulfolobus solfataricus can transfer the propylamine moiety from S-adenosyl 3-(methylsulfanyl)propylamine to putrescine, sym-norspermidine and spermidine with lower efficiency [3]. cf. EC (spermidine synthase) and EC (spermine synthase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050314


  1. Aleksijevic, A., Grove, J. and Schuber, F.
    Studies on polyamine biosynthesis in Euglena gracilis.
    Biochim. Biophys. Acta 565 : 199-207 (1979). [PMID: 116684]
  2. Villanueva, V.R., Adlakha, R.C. and Calbayrac, R.
    Biosynthesis of polyamines in Euglena gracilis.
    Phytochemistry 19 : 787-790 (1980).

[EC created 1983, modified 2013]