EC 2.5.1.140 - N-(2-amino-2-carboxyethyl)-L-glutamate synthase

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IntEnz Enzyme Nomenclature
EC 2.5.1.140

Names

Accepted name:
N-(2-amino-2-carboxyethyl)-L-glutamate synthase
Other names:
SbnA
ACEGA synthase
Systematic name:
O-phospho-L-serine:L-glutamate N-(2S)-2-amino-2-carboxyethyltransferase

Reaction

Comments:

The enzyme, characterized from the bacterium Staphylococcus aureus, is involved in the biosynthesis of the siderophore staphyloferrin B.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (20) [show] [UniProt]

References

  1. Beasley, F. C., Cheung, J., Heinrichs, D. E.
    Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus.
    BMC Microbiol. 11: 199 (2011). [PMID: 21906287]
  2. Kobylarz, M. J., Grigg, J. C., Takayama, S. J., Rai, D. K., Heinrichs, D. E., Murphy, M. E.
    Synthesis of L-2,3-diaminopropionic acid, a siderophore and antibiotic precursor.
    Chem. Biol. 21: 379-388 (2014). [PMID: 24485762]

[EC 2.5.1.140 created 2017]