EC 2.5.1.134 - Cystathionine β-synthase (O-acetyl-L-serine)

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.5.1.134

Names

Accepted name:
cystathionine β-synthase (O-acetyl-L-serine)
Other names:
MccB
O-acetylserine dependent cystathionine β-synthase
Systematic name:
O-acetyl-L-serine:L-homocysteine 2-amino-2-carboxyethyltransferase

Reaction

Cofactor

Comments:

A pyridoxal 5'-phosphate protein. The enzyme, purified from the bacterium Bacillus subtilis, also has a low activity with L-serine (cf. EC 4.2.1.22, cystathionine β-synthase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Hullo, M. F., Auger, S., Soutourina, O., Barzu, O., Yvon, M., Danchin, A., Martin-Verstraete, I.
    Conversion of methionine to cysteine in Bacillus subtilis and its regulation.
    J. Bacteriol. 189: 187-197 (2007). [PMID: 17056751]

[EC 2.5.1.134 created 2016]