EC 2.5.1.133 - Bacteriochlorophyll a synthase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.5.1.133

Names

Accepted name:
bacteriochlorophyll a synthase
Other name:
bchG (gene name)
Systematic name:
geranylgeranyl-diphosphate:bacteriochlorophyllide-a geranyltransferase

Reaction

Comments:

The enzyme catalyses the addition of a geranylgeranyl hydrophobic chain to bacteriochlorophyllide a via an ester bond with the 17-propionate residue. The side chain is later modified to a phytyl chain, resulting in bacteriochlorophyll a.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Oster, U., Bauer, C. E., Rudiger, W.
    Characterization of chlorophyll a and bacteriochlorophyll a synthases by heterologous expression in Escherichia coli.
    J. Biol. Chem. 272 : 9671-9676 (1997). [PMID: 9092496]
  2. Addlesee, H. A., Fiedor, L., Hunter, C. N.
    Physical mapping of bchG, orf427, and orf177 in the photosynthesis gene cluster of Rhodobacter sphaeroides: functional assignment of the bacteriochlorophyll synthetase gene.
    J. Bacteriol. 182 : 3175-3182 (2000). [PMID: 10809697]
  3. Garcia-Gil, L. J., Gich, F. B., Fuentes-Garcia, X.
    A comparative study of bchG from green photosynthetic bacteria.
    Arch. Microbiol. 179 : 108-115 (2003). [PMID: 12560989]
  4. Saga, Y., Hirota, K., Harada, J., Tamiaki, H.
    In Vitro Enzymatic Activities of Bacteriochlorophyll a Synthase Derived from the Green Sulfur Photosynthetic Bacterium Chlorobaculum tepidum.
    Biochemistry 54 : 4998-5005 (2015). [PMID: 26258685]

[EC 2.5.1.133 created 2016]