EC 2.5.1.107 - Verruculogen prenyltransferase

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IntEnz Enzyme Nomenclature
EC 2.5.1.107

Names

Accepted name:
verruculogen prenyltransferase
Other name:
FtmPT3
Systematic name:
dimethylallyl-diphosphate:verruculogen dimethylallyl-O-transferase

Reaction

Comments:

Found in a number of fungi. Catalyses the last step in the biosynthetic pathway of the indole alkaloid fumitremorgin A. The enzyme from the fungus Neosartorya fischeri is also active with fumitremorgin B and 12α,13α-dihydroxyfumitremorgin C.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Mundt, K., Wollinsky, B., Ruan, H. L., Zhu, T., Li, S. M.
    Identification of the verruculogen prenyltransferase FtmPT3 by a combination of chemical, bioinformatic and biochemical approaches.
    Chembiochem 13 : 2583-2592 (2012). [PMID: 23109474]

[EC 2.5.1.107 created 2013]