EC 2.4.99.5 - Galactosyldiacylglycerol α-2,3-sialyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.99.5

Names

Accepted name:
galactosyldiacylglycerol α-2,3-sialyltransferase
Systematic name:
CMP-N-acetyl-β-neuraminate:1,2-diacyl-3-β-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase

Reaction

Comments:

The β-D-galactosyl residue of the oligosaccharide of glycoproteins may also act as acceptor.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047289
CAS Registry Number: 80237-98-5

References

  1. Pieringer, J., Keech, S. and Pieringer, R.A.
    Biosynthesis in vitro of sialosylgalactosyldiacylglycerol by mouse brain microsomes.
    J. Biol. Chem. 256: 12306-12309 (1981). [PMID: 7298658]
  2. Weinstein, J., de Souza-e-Silva, U. and Paulson, J.C.
    Purification of a Gal β1→4GlcNAc α2→6 sialyltransferase and a Gal β1→3(4)GlcNAc α2→3 sialyltransferase to homogeneity from rat liver.
    J. Biol. Chem. 257: 13835-13844 (1982). [PMID: 7142179]
  3. Weinstein, J., de Souza-e-Silva, U. and Paulson, J.C.
    Sialylation of glycoprotein oligosaccharides N-linked to asparagine. Enzymatic characterization of a Gal β1→3(4)GlcNAc α2→3 sialyltransferase and a Gal β1→4GlcNAc α2→6 sialyltransferase from rat liver.
    J. Biol. Chem. 257: 13845-13853 (1982). [PMID: 7142180]

[EC 2.4.99.5 created 1984, modified 1986]