EC - β-galactoside α-2,3-sialyltransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
β-galactoside α-2,3-sialyltransferase
Other names:
CMP-N-acetylneuraminate:β-D-galactoside α-2,3-N-acetylneuraminyl-transferase
Systematic name:
CMP-N-acetylneuraminate:β-D-galactoside α-(2→3)-N-acetylneuraminyl-transferase



The acceptor is Galβ1,3GalNAc-R, where R is H, a threonine or serine residue in a glycoprotein, or a glycolipid. Lactose can also act as acceptor. May be identical with EC monosialoganglioside sialyltransferase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0003836
CAS Registry Number: 71124-51-1
UniProtKB/Swiss-Prot: (19) [show] [UniProt]


  1. Rearick, J.I., Sadler, J.E., Paulson, J.C. and Hill, R.L.
    Enzymatic characterization of β D-galactoside α2→3 sialyltransferase from porcine submaxillary gland.
    J. Biol. Chem. 254 : 4444-4451 (1979). [PMID: 438198]
  2. Sadler, J.E., Rearick, J.I., Paulson, J.C. and Hill, R.L.
    Purification to homogeneity of a β-galactoside α2→3 sialyltransferase and partial purification of an α-N-acetylgalactosaminide α2→6 sialyltransferase from porcine submaxillary glands.
    J. Biol. Chem. 254 : 4434-4442 (1979). [PMID: 438196]

[EC created 1984, modified 1986]