EC 2.4.99.3 - α-N-acetylgalactosaminide α-2,6-sialyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.99.3

Names

Accepted name:
α-N-acetylgalactosaminide α-2,6-sialyltransferase
Systematic name:
CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-α-D-galactosaminyl)-glycoprotein α-2,6-N-acetylneuraminyltransferase

Reaction

Comments:

α-N-Acetylgalactosamine linked to threonine or serine is also an acceptor, when substituted at the 3-position.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0001665
CAS Registry Number: 71124-50-0
UniProtKB/Swiss-Prot:

References

  1. Sadler, J.E., Rearick, J.I. and Hill, R.L.
    Purification to homogeneity and enzymatic characterization of an α-N-acetylgalactosaminide α2→6 sialyltransferase from porcine submaxillary glands.
    J. Biol. Chem. 254: 5934-5941 (1979). [PMID: 447688]

[EC 2.4.99.3 created 1984, modified 1986]