EC 2.4.2.58 - Hydroxyproline O-arabinosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.2.58

Names

Accepted name:
hydroxyproline O-arabinosyltransferase
Other name:
HPAT
Systematic name:
UDP-β-L-arabinofuranose:[protein]-trans-4-hydroxy-L-proline L-arabinofuranosyl transferase (configuration-retaining)

Reaction

Comments:

The enzyme, found in plants and mosses, catalyses the O-arabinosylation of hydroxyprolines in hydroxyproline-rich glycoproteins. The enzyme acts on the first hydroxyproline in the motif Val-hydroxyPro-hydroxyPro-Ser.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Ogawa-Ohnishi, M., Matsushita, W., Matsubayashi, Y.
    Identification of three hydroxyproline O-arabinosyltransferases in Arabidopsis thaliana.
    Nat. Chem. Biol. 9 : 726-730 (2013). [PMID: 24036508]

[EC 2.4.2.58 created 2016]