EC 2.4.2.45 - Decaprenyl-phosphate phosphoribosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.2.45

Names

Accepted name:
decaprenyl-phosphate phosphoribosyltransferase
Other names:
5-phospho-α-D-ribose-1-diphosphate:decaprenyl-phosphate 5-phosphoribosyltransferase
5-phospho-α-D-ribose 1-pyrophosphate:decaprenyl phosphate 5-phosphoribosyltransferase
DPPR synthase
Rv3806
Systematic name:
trans,octacis-decaprenylphospho-β-D-ribofuranose 5-phosphate:diphosphate phospho-α-D-ribosyltransferase

Reaction

Cofactor

Comments:

Requires Mg2+. Isolated from Mycobacterium tuberculosis. Has some activity with other polyprenyl phosphates.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Huang, H., Scherman, M. S., D'Haeze, W., Vereecke, D., Holsters, M., Crick, D. C., McNeil, M. R.
    Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-alpha-D-ribose-L-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-D-arabinose synthesis.
    J. Biol. Chem. 280: 24539-24543 (2005). [PMID: 15878857]

[EC 2.4.2.45 created 2012]