EC - Thymidine phosphorylase

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IntEnz Enzyme Nomenclature


Accepted name:
thymidine phosphorylase
Other names:
animal growth regulators, blood platelet-derived endothelial cell growth factors
blood platelet-derived endothelial cell growth factor
deoxythymidine phosphorylase
pyrimidine deoxynucleoside phosphorylase
pyrimidine phosphorylase
thymidine-orthophosphate deoxyribosyltransferase
thymidine:phosphate deoxy-D-ribosyltransferase
Systematic name:
thymidine:phosphate deoxy-α-D-ribosyltransferase



The enzyme in some tissues also catalyses deoxyribosyltransferase reactions of the type catalysed by EC, nucleoside deoxyribosyltransferase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00557
Structural data: CSA , EC2PDB
Gene Ontology: GO:0009032
CAS Registry Number: 9030-23-3
UniProtKB/Swiss-Prot: (144) [show] [UniProt]


  1. Friedkin, M. and Roberts, D.
    The enzymatic synthesis of nucleosides. I. Thymidine phosphorylase in mammalian tissue.
    J. Biol. Chem. 207 : 245-256 (1954). [PMID: 13152099]
  2. Zimmerman, M. and Seidenberg, J.
    Deoxyribosyl transfer. I. Thymidine phosphorylase and nucleoside deoxyribosyltransferase in normal and malignant tissues.
    J. Biol. Chem. 239 : 2618-2621 (1964). [PMID: 14235544]
  3. Zimmerman, M.
    Deoxyribosyl transfer. II. Nucleoside:pyrimidine deoxyribosyltransferase activity of three partially purified thymidine phosphorylases.
    J. Biol. Chem. 239 : 2622-2627 (1964). [PMID: 14235545]

[EC created 1961]