EC - S-methyl-5'-thioadenosine phosphorylase

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IntEnz Enzyme Nomenclature


Accepted name:
S-methyl-5'-thioadenosine phosphorylase
Other names:
5'-deoxy-5'-methylthioadenosine phosphorylase
5'-methylthioadenosine phosphorylase
5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase
MTA phosphorylase
MeSAdo phosphorylase
MeSAdo/Ado phosphorylase
methylthioadenosine nucleoside phosphorylase
methylthioadenosine phosphorylase
S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-α-D-ribosyl-transferase
Systematic name:
S-methyl-5'-thioadenosine:phosphate S-methyl-5-thio-α-D-ribosyl-transferase



Also acts on 5'-deoxyadenosine and other analogues having 5'-deoxy groups.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00946 , PROSITE:PDOC00954
Structural data: CSA , EC2PDB
Gene Ontology: GO:0017061
CAS Registry Number: 61970-06-7
UniProtKB/Swiss-Prot: (105) [show] [UniProt]


  1. Carteni-Farina, M., Oliva, A., Romeo, G., Napolitano, G., De Rosa, M., Gambacorta, A. and Zappia, V.
    5'-Methylthioadenosine phosphorylase from Caldariella acidophila. Purification and properties.
    Eur. J. Biochem. 101 : 317-324 (1979). [PMID: 118001]
  2. Garbers, D.L.
    Demonstration of 5'-methylthioadenosine phosphorylase activity in various rat tissues. Some properties of the enzyme from rat lung.
    Biochim. Biophys. Acta 523 : 82-93 (1978). [PMID: 415762]
  3. Pegg, A.E. and Williams-Ashman, H.G.
    Phosphate-stimulated breakdown of 5'-methylthioadenosine by rat ventral prostate.
    Biochem. J. 115 : 241-247 (1969). [PMID: 5378381]

[EC created 1983]