EC 2.4.1.80 - Ceramide glucosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.1.80

Names

Accepted name:
ceramide glucosyltransferase
Other names:
UDP-glucose:ceramide glucosyltransferase
UDPglucose:N-acylsphingosine D-glucosyltransferase
ceramide:UDP-glucose glucosyltransferase
ceramide:UDPGlc glucosyltransferase
glucosylceramide synthase
uridine diphosphoglucose-ceramide glucosyltransferase
UDP-glucose-ceramide glucosyltransferase
Systematic name:
UDP-glucose:N-acylsphingosine D-glucosyltransferase

Reaction

Comments:

Sphingosine and dihydrosphingosine can also act as acceptors; CDP-glucose can act as donor.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008120 , GO:0102769
CAS Registry Number: 37237-44-8
UniProtKB/Swiss-Prot: (14) [show] [UniProt]

References

  1. Basu, S., Kaufman, B. and Roseman, S.
    Enzymatic synthesis of glucocerebroside by a glucosyltransferase from embryonic chicken brain.
    J. Biol. Chem. 248: 1388-1394 (1973). [PMID: 4631392]

[EC 2.4.1.80 created 1976]