EC - Validoxylamine A glucosyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
validoxylamine A glucosyltransferase
Other names:
vldK (gene name)
valG (gene name)
Systematic name:
UDP-α-D-glucose:validoxylamine-A D-glucosyltransferase



The enzyme, characterized from the bacterium Streptomyces hygroscopicus subsp. limoneus, catalyses the ultimate step in the biosynthesis of the antifungal agent validamycin A.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Bai, L., Li, L., Xu, H., Minagawa, K., Yu, Y., Zhang, Y., Zhou, X., Floss, H. G., Mahmud, T., Deng, Z.
    Functional analysis of the validamycin biosynthetic gene cluster and engineered production of validoxylamine A.
    Chem. Biol. 13: 387-397 (2006). [PMID: 16632251]
  2. Xu, H., Minagawa, K., Bai, L., Deng, Z., Mahmud, T.
    Catalytic analysis of the validamycin glycosyltransferase (ValG) and enzymatic production of 4''-epi-validamycin A.
    J. Nat. Prod. 71: 1233-1236 (2008). [PMID: 18563934]

[EC created 2016]