EC 2.4.1.325 - TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase
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IntEnz Enzyme Nomenclature
EC 2.4.1.325
Names
Accepted name:
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase
Other
names:
TDP-Fuc4NAc:lipid II Fuc4NAc-transferase
TDP-Fuc4NAc:lipid II Fuc4NAc transferase
wecF (gene name)
TDP-Fuc4NAc:lipid II Fuc4NAc transferase
wecF (gene name)
Systematic name:
dTDP-N-acetyl-α-D-fucose:N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol N-acetylfucosaminyltransferase
Reaction
- dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + N-acetyl-beta-D-mannosaminouronyl-(1right4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = dTDP + 4-acetamido-4,6-dideoxy-alpha-D-galactosyl-(1right4)-N-acetyl-beta-D-mannosaminouronyl-(1right4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
Comments:
Involved in the enterobacterial common antigen (ECA) biosynthesis in the bacterium Escherichia coli. The trisaccharide of the product (lipid III) is the repeat unit of ECA.
Links to other databases
Gene Ontology:
GO:0102031
References
-
Identification of the structural gene for the TDP-Fuc4NAc:lipid II Fuc4NAc transferase involved in synthesis of enterobacterial common antigen in Escherichia coli K-12.J. Bacteriol. 183 : 6509-6516 (2001). [PMID: 11673418]
[EC 2.4.1.325 created 2014]