EC - TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase
Other names:
TDP-Fuc4NAc:lipid II Fuc4NAc-transferase
TDP-Fuc4NAc:lipid II Fuc4NAc transferase
wecF (gene name)
Systematic name:
dTDP-N-acetyl-α-D-fucose:N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol N-acetylfucosaminyltransferase



Involved in the enterobacterial common antigen (ECA) biosynthesis in the bacterium Escherichia coli. The trisaccharide of the product (lipid III) is the repeat unit of ECA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102031
UniProtKB/Swiss-Prot: (58) [show] [UniProt]


  1. Rahman, A., Barr, K., Rick, P. D.
    Identification of the structural gene for the TDP-Fuc4NAc:lipid II Fuc4NAc transferase involved in synthesis of enterobacterial common antigen in Escherichia coli K-12.
    J. Bacteriol. 183 : 6509-6516 (2001). [PMID: 11673418]

[EC created 2014]