EC - 2-deoxystreptamine glucosyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
2-deoxystreptamine glucosyltransferase
Other name:
kanF (gene name)
Systematic name:
UDP-α-D-glucose:2-deoxystreptamine 6-α-D-glucosyltransferase



Involved in the biosynthesis of kanamycin B and kanamycin C. Also catalyses EC, 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase, but activity is only one fifth of that with UDP-α-D-glucose.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102318


  1. Park, J. W., Park, S. R., Nepal, K. K., Han, A. R., Ban, Y. H., Yoo, Y. J., Kim, E. J., Kim, E. M., Kim, D., Sohng, J. K., Yoon, Y. J.
    Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
    Nat. Chem. Biol. 7 : 843-852 (2011). [PMID: 21983602]

[EC created 2012]