EC 2.4.1.284 - 2-deoxystreptamine glucosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.1.284

Names

Accepted name:
2-deoxystreptamine glucosyltransferase
Other name:
kanF (gene name)
Systematic name:
UDP-α-D-glucose:2-deoxystreptamine 6-α-D-glucosyltransferase

Reaction

Comments:

Involved in the biosynthesis of kanamycin B and kanamycin C. Also catalyses EC 2.4.1.283, 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase, but activity is only one fifth of that with UDP-α-D-glucose.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102318
UniProtKB/Swiss-Prot:

References

  1. Park, J. W., Park, S. R., Nepal, K. K., Han, A. R., Ban, Y. H., Yoo, Y. J., Kim, E. J., Kim, E. M., Kim, D., Sohng, J. K., Yoon, Y. J.
    Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
    Nat. Chem. Biol. 7 : 843-852 (2011). [PMID: 21983602]

[EC 2.4.1.284 created 2012]