EC 2.4.1.254 - Cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.1.254

Names

Accepted name:
cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase
Other names:
BpUGT94B1
UDP-glucuronic acid:anthocyanin glucuronosyltransferase
UDP-glucuronic acid:anthocyanidin 3-glucoside 2'-O-β-glucuronosyltransferase
BpUGAT
Systematic name:
UDP-α-D-glucuronate:cyanidin-3-O-β-D-glucoside 2-O-β-glucuronosyltransferase

Reaction

Comments:

The enzyme is highly specific for cyanidin 3-O-glucosides and UDP-α-D-glucuronate. Involved in the production of glucuronosylated anthocyanins that are the origin of the red coloration of flowers of Bellis perennis [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00359
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102160
UniProtKB/Swiss-Prot:

References

  1. Sawada, S., Suzuki, H., Ichimaida, F., Yamaguchi, M. A., Iwashita, T., Fukui, Y., Hemmi, H., Nishino, T., Nakayama, T.
    UDP-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (Bellis perennis) flowers. Enzymology and phylogenetics of a novel glucuronosyltransferase involved in flower pigment biosynthesis.
    J. Biol. Chem. 280 : 899-906 (2005). [PMID: 15509561]
  2. Osmani, S. A., Bak, S., Imberty, A., Olsen, C. E., Møller, B. L.
    Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses.
    Plant Physiol. 148 : 1295-1308 (2008). [PMID: 18829982]

[EC 2.4.1.254 created 2011]