EC 2.4.1.19 - Cyclomaltodextrin glucanotransferase

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IntEnz Enzyme Nomenclature
EC 2.4.1.19

Names

Accepted name:
cyclomaltodextrin glucanotransferase
Other names:
α-1,4-glucan 4-glycosyltransferase, cyclizing
α-cyclodextrin glucanotransferase
α-cyclodextrin glycosyltransferase
β-cyclodextrin glycosyltransferase
γ-cyclodextrin glycosyltransferase
Bacillus macerans amylase
BMA
CGTase
cyclodextrin glucanotransferase
cyclodextrin glycosyltransferase
cyclomaltodextrin glucotransferase
cyclomaltodextrin glycosyltransferase
konchizaimu
neutral-cyclodextrin glycosyltransferase
1,4-α-D-glucan 4-α-D-(1,4-α-D-glucano)-transferase (cyclizing)
Systematic name:
(1→4)-α-D-glucan:(1→4)-α-D-glucan 4-α-D-[(1→4)-α-D-glucano]-transferase (cyclizing)

Reaction

Comments:

Cyclomaltodextrins (Schardinger dextrins) of various sizes (6,7,8, etc. glucose units) are formed reversibly from starch and similar substrates. Will also disproportionate linear maltodextrins without cyclizing (cf. EC 2.4.1.25, 4-α-glucanotransferase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC51166
Structural data: CSA , EC2PDB
Gene Ontology: GO:0043895
CAS Registry Number: 9030-09-5
UniProtKB/Swiss-Prot: (16) [show] [UniProt]

References

  1. DePinto, J.A. and Campbell, L.L.
    Purification and properties of the amylase of Bacillus macerans.
    Biochemistry 7: 114-120 (1968). [PMID: 5758537]
  2. French, D., Levine, M.L., Norberg, E., Norden, P., Pazur, J.H. and Wild, G.M.
    Studies on the Schardinger dextrins. VII. Co-substrate specificity in coupling reactions of Macerans amylase.
    J. Am. Chem. Soc. 76: 2387-2390 (1954).
  3. Hehre, E.J.
    Enzymic synthesis of polysaccharides: a biological type of polymerization.
    Adv. Enzymol. Relat. Subj. Biochem. 11: 297-337 (1951).
  4. Schwimmer, S.
    Evidence for the purity of Schardinger dextrinogenase.
    Arch. Biochem. Biophys. 43: 108-117 (1953).

[EC 2.4.1.19 created 1961]