EC 2.4.1.187 - N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-β-D-mannosaminyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.1.187

Names

Accepted name:
N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-β-D-mannosaminyltransferase
Other names:
N-acetylmannosaminyltransferase
UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase
uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase
UDP-N-acetyl-D-mannosamine:N-acetyl-β-D-glucosaminyldiphosphoundecaprenol β-1,4-N-acetylmannosaminyltransferase
UDP-N-acetyl-D-mannosamine:N-acetyl-β-D-glucosaminyldiphosphoundecaprenol 4-β-4-N-acetylmannosaminyltransferase
UDP-N-acetyl-α-D-mannosamine:N-acetyl-β-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-β-4-N-acetylmannosaminyltransferase
tagA (gene name)
tarA (gene name)
Systematic name:
UDP-N-acetyl-α-D-mannosamine:N-acetyl-α-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol 4-β-N-acetylmannosaminyltransferase (configuration-inverting)

Reaction

Comments:

Involved in the biosynthesis of teichoic acid linkage units in bacterial cell walls.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047244
CAS Registry Number: 118731-82-1
UniProtKB/Swiss-Prot: (10) [show] [UniProt]

References

  1. Murazumi, N., Kumita, K., Araki, Y. and Ito, E.
    Partial purification and properties of UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase from Bacillus subtilis.
    J. Biochem. (Tokyo) 104 : 980-984 (1988). [PMID: 2977387]
  2. Ginsberg, C., Zhang, Y. H., Yuan, Y., Walker, S.
    In vitro reconstitution of two essential steps in wall teichoic acid biosynthesis.
    ACS Chem. Biol. 1 : 25-28 (2006). [PMID: 17163636]
  3. Zhang, Y. H., Ginsberg, C., Yuan, Y., Walker, S.
    Acceptor substrate selectivity and kinetic mechanism of Bacillus subtilis TagA.
    Biochemistry 45 : 10895-10904 (2006). [PMID: 16953575]

[EC 2.4.1.187 created 1992, modified 2016]