EC 2.4.1.179 - Lactosylceramide β-1,3-galactosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.1.179

Names

Accepted name:
lactosylceramide β-1,3-galactosyltransferase
Other names:
UDP-galactose:D-galactosyl-1,4-β-D-glucosyl-R β-1,3-galactosyltransferase
uridine diphosphogalactose-lactosylceramide β1→3-galactosyltransferase
UDP-galactose:D-galactosyl-(1→4)-β-D-glucosyl-R 3-β-galactosyltransferase
Systematic name:
UDP-α-D-galactose:D-galactosyl-(1→4)-β-D-glucosyl-R 3-β-galactosyltransferase

Reaction

Comments:

R may be an oligosaccharide or a glycolipid; lactose can also act as acceptor, but more slowly. Involved in the elongation of oligosaccharide chains, especially in glycolipids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047240
CAS Registry Number: 106769-64-6

References

  1. Bailly, P., Piller, F. and Cartron, J.-P.
    Characterization and specific assay for a galactoside β-3-galactosyltransferase of human kidney.
    Eur. J. Biochem. 173: 417-422 (1988). [PMID: 3129295]

[EC 2.4.1.179 created 1989]