EC 2.4.1.164 - Galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,6-N-acetylglucosaminyltransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.4.1.164

Names

Accepted name:
galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,6-N-acetylglucosaminyltransferase
Other names:
uridine diphosphoacetylglucosamine-acetyllactosaminide β1→6-acetylglucosaminyltransferase
UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide β-1,6-N-acetylglucosaminyltransferase
UDP-N-acetyl-D-glucosamine:D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide 6-β-N-acetylglucosaminyltransferase
Systematic name:
UDP-N-acetyl-α-D-glucosamine:β-D-Gal-(1→4)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-β-D-Glc-(1↔1)-ceramide 6-β-N-acetylglucosaminyltransferase (conformation-inverting)

Reaction

Comments:

Requires Mn2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047232

References

  1. Basu, M. and Basu, S.
    Biosynthesis in vitro of Ii core glycosphingolipids from neolactotetraosylceramide by β1-3- and β1-6-N-acetylglucosaminyltransferases from mouse T-lymphoma.
    J. Biol. Chem. 259: 12557-12562 (1984). [PMID: 6238026]

[EC 2.4.1.164 created 1989]