EC 2.3.3.6 - 2-ethylmalate synthase

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IntEnz Enzyme Nomenclature
EC 2.3.3.6

Names

Accepted name:
2-ethylmalate synthase
Other names:
(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating)
2-ethylmalate-3-hydroxybutanedioate synthase
propylmalate synthase
propylmalic synthase
Systematic name:
acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)

Reaction

Comments:

Also acts on (R)-2-(n-propyl)-malate. Formerly wrongly included with EC 2.3.3.7, 3-ethylmalate synthase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050438
CAS Registry Number: 9024-01-5

References

  1. Strassman, M. and Ceci, L.N.
    A study of acetyl-CoA condensation with α-keto acids.
    Arch. Biochem. Biophys. 119: 420-428 (1967). [PMID: 6052435]

[EC 2.3.3.6 created 1983 as EC 4.1.3.33, transferred 2002 to EC 2.3.3.6]