EC 2.3.3.4 - Decylhomocitrate synthase

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IntEnz Enzyme Nomenclature
EC 2.3.3.4

Names

Accepted name:
decylhomocitrate synthase
Other names:
2-decylhomocitrate synthase
3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating)
Systematic name:
dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)

Reaction

Comments:

Decanoyl-CoA can act instead of dodecanoyl-CoA, but 2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050458
CAS Registry Number: 51845-40-0

References

  1. Måhlén, A.
    Purification and some properties of 2-decylhomocitrate synthase from Penicillium spiculisporum.
    Eur. J. Biochem. 38: 32-39 (1973). [PMID: 4774124]
  2. Brandäge, S., Dahlman, O., Lindqvist, B., Måhlén, A. and Mörch, L.
    Absolute configuration and enantiospecific synthesis of spiculisporic acid.
    Acta Chem. Scand. 38B: 837-844 (1984).

[EC 2.3.3.4 created 1976 as EC 4.1.3.29, transferred 2002 to EC 2.3.3.4]