EC 2 - Transferases
EC 2.3 - Acyltransferases
EC 2.3.3 - Acyl groups converted into alkyl groups on transfer
EC 2.3.3.16 - Citrate synthase (unknown stereospecificity)
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 2.3.3.16
Names
Accepted name:
citrate synthase (unknown stereospecificity)
Other
names:
citrate condensing enzyme
CoA-acetylating citrate oxaloacetate-lyase
citrate synthetase
citric synthase
citric-condensing enzyme
citrogenase
condensing enzyme [ambiguous]
oxaloacetate transacetase
oxalacetic transacetase
CoA-acetylating citrate oxaloacetate-lyase
citrate synthetase
citric synthase
citric-condensing enzyme
citrogenase
condensing enzyme [ambiguous]
oxaloacetate transacetase
oxalacetic transacetase
Systematic name:
acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
Reaction
- acetyl-CoA + H2O + oxaloacetate = citrate + CoA
Comments:
This entry has been included to accommodate those citrate synthases for which the stereospecificity with respect to C2 of oxaloacetate has not been established [cf. EC 2.3.3.1, citrate (Si)-synthase and EC 2.3.3.3, citrate (Re)-synthase].
Links to other databases
References
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Purification and properties of an archaebacterial enzyme: citrate synthase from Sulfolobus solfataricus.Biol. Chem. Hoppe-Seyler 369 : 109-113 (1988). [PMID: 3130075]
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Purification and properties of citrate synthase from Acetobacter europaeus.FEMS Microbiol. Lett. 146 : 53-58 (1997). [PMID: 8997706]
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Purification and characterization of citrate synthase from Methylobacterium extorquens—a methylotrophic producer of polyhydroxybutyrate.Biochemistry (Mosc.) 62 : 71-76 (1997). [PMID: 9113733]
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Characterization of citrate synthase purified from Drosophila melanogaster.Mol. Cells 7 : 599-604 (1997). [PMID: 9387145]
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Insights into the evolution of allosteric properties. The NADH binding site of hexameric type II citrate synthases.Biochemistry 42 : 5555-5565 (2003). [PMID: 12741811]
[EC 2.3.3.16 created 2014]