EC 2.3.1.93 - 13-hydroxylupanine O-tigloyltransferase

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IntEnz Enzyme Nomenclature
EC 2.3.1.93

Names

Accepted name:
13-hydroxylupanine O-tigloyltransferase
Other names:
13-hydroxylupanine acyltransferase
tigloyl-CoA:13-hydroxylupanine O-tigloyltransferase
Systematic name:
(E)-2-methylcrotonoyl-CoA:13-hydroxylupanine O-2-methylcrotonoyltransferase

Reaction

Comments:

Benzoyl-CoA and, more slowly, pentanoyl-CoA, 3-methylbutanoyl-CoA and butanoyl-CoA can act as acyl donors. Involved in the synthesis of lupanine alkaloids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047203
CAS Registry Number: 85341-00-0
UniProtKB/Swiss-Prot:

References

  1. Wink, M. and Hartmann, T.
    Enzymatic synthesis of quinolizidine alkaloid esters: a tigloyl-CoA:13-hydroxylupanine O-tigloyl transferase from Lupinus albus L.
    Planta 156: 560-565 (1982).
  2. Okada, T.. Hirai, M.Y., Suzuki, H., Yamazaki, M. and Saito, K.
    Molecular characterization of a novel quinolizidine alkaloid O-tigloyltransferase: cDNA cloning, catalytic activity of recombinant protein and expression analysis in Lupinus plants.
    Plant Cell Physiol. 46: 233-244 (2005).
  3. Suzuki, H., Murakoshi, I., Saito, K.
    A novel O-tigloyltransferase for alkaloid biosynthesis in plants. Purification, characterization, and distribution in Lupinus plants.
    J. Biol. Chem. 269: 15853-15860 (1994). [PMID: 8195240]

[EC 2.3.1.93 created 1986, modified 2011]