EC - Diacylglycerol—sterol O-acyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
diacylglycerol—sterol O-acyltransferase
Other name:
1,2-diacyl-sn-glycerol:sterol acyl transferase
Systematic name:
1,2-diacyl-sn-glycerol:sterol O-acyltransferase



Cholesterol, sitosterol, campesterol and diacylglycerol can act as acceptors. Transfers a number of long-chain fatty acyl groups.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047195
CAS Registry Number: 79586-23-5


  1. Bartlett, K., Keat, M.J. and Mercer, E.I.
    Biosynthesis of sterol esters in Phycomyces blakesleeanus.
    Phytochemistry 13 : 1107-1113 (1974).
  2. Garcia, R.E. and Mudd, J.B.
    Metabolism of monoacylglycerol and diacylglycerol by enzyme preparations from spinach leaves.
    Arch. Biochem. Biophys. 191 : 487-493 (1978). [PMID: 742884]
  3. Garcia, R.E. and Mudd, J.B.
    1,2-Diacyl-sn-glycerol:sterol acyl transferase from spinach leaves (Spinacia oleracea L.).
    Methods Enzymol. 71 : 768-772 (1981).

[EC created 1984]