IntEnz

EC 2.3.1.57 - Diamine N-acetyltransferase

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IntEnz Enzyme Nomenclature
EC 2.3.1.57

Names

Accepted name:

diamine N-acetyltransferase

Other names:

acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase
diamine acetyltransferase
putrescine (diamine)-acetylating enzyme
putrescine N-acetyltransferase
putrescine acetylase
putrescine acetyltransferase
spermidine N¹-acetyltransferase
spermidine acetyltransferase
spermidine/spermine N¹-acetyltransferase

Systematic name:

acetyl-CoA:alkane-α,ω-diamine N-acetyltransferase

Reaction

acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine

Comments:

Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N1- and N8-acetylspermidine), spermine, N1-acetylspermidine and N8-acetylspermidine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Structural data: CSA , EC2PDB

Gene Ontology: GO:0004145

CAS Registry Number: 54596-36-0

UniProtKB/Swiss-Prot: (24) [show] [UniProt]

References

Della Ragione, F. and Pegg, A.E.

Purification and characterization of spermidine/spermine N¹-acetyltransferase from rat liver.

Biochemistry 21 : 6152-6158 (1982). [PMID: 7150547]

[EC 2.3.1.57 created 1976, modified 1989]

EC 2 - Transferases