EC - Glycerone-phosphate O-acyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
glycerone-phosphate O-acyltransferase
Other name:
dihydroxyacetone phosphate acyltransferase
Systematic name:
acyl-CoA:glycerone-phosphate O-acyltransferase



A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0016287
CAS Registry Number: 37257-19-5


  1. Ballas, L.M. and Bell, R.M.
    Topography of glycerolipid synthetic enzymes. Synthesis of phosphatidylserine, phosphatidylinositol and glycerolipid intermediates occurs on the cytoplasmic surface of rat liver microsomal vesicles.
    Biochim. Biophys. Acta 665: 586-595 (1981). [PMID: 6271231]
  2. Declercq, P.E., Haagsman, H.P., Van Veldhoven, P., Debeer, L.J., Van Golde, L.M.G. and Mannaerts, G.P.
    Rat liver dihydroxyacetone-phosphate acyltransferases and their contribution to glycerolipid synthesis.
    J. Biol. Chem. 259: 9064-9075 (1984).
  3. Hajra, A.K.
    Biosynthesis of acyl dihydroxyacetone phosphate in guinea pig liver mitochondria.
    J. Biol. Chem. 243: 3458-3465 (1968). [PMID: 5656381]

[EC created 1972]