EC 2.3.1.280 - (aminoalkyl)phosphonate N-acetyltransferase

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IntEnz Enzyme Nomenclature
EC 2.3.1.280

Names

Accepted name:
(aminoalkyl)phosphonate N-acetyltransferase
Systematic name:
acetyl-CoA:(aminomethyl)phosphonate N-acetyltransferase

Reactions

Comments:

The enzyme, characterized from the bacterium Escherichia coli, is able to acetylate a range of (aminoalkyl)phosphonic acids. Requires a divalent metal ion for activity.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Errey, J. C., Blanchard, J. S.
    Functional annotation and kinetic characterization of PhnO from Salmonella enterica.
    Biochemistry 45 : 3033-3039 (2006). [PMID: 16503658]
  2. Hove-Jensen, B., McSorley, F. R., Zechel, D. L.
    Catabolism and detoxification of 1-aminoalkylphosphonic acids: N-acetylation by the phnO gene product.
    PLoS ONE 7 : e46416 (2012). [PMID: 23056305]

[EC 2.3.1.280 created 2018]