EC - Galactosamine-1-phosphate N-acetyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
galactosamine-1-phosphate N-acetyltransferase
Other name:
ST0452 (locus name)
Systematic name:
acetyl-CoA:α-D-galactosamine-1-phosphate N-acetyltransferase



The enzyme, characterized from the archaeon Sulfolobus tokodaii, is also active toward α-D-glucosamine 1-phosphate (cf. EC, glucosamine-1-phosphate N-acetyltransferase). In addition, that enzyme contains a second domain that catalyses the activities of EC, UDP-N-acetylglucosamine diphosphorylase, EC, glucose-1-phosphate thymidylyltransferase, and EC, UDP-N-acetylgalactosamine diphosphorylase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Zhang, Z., Tsujimura, M., Akutsu, J., Sasaki, M., Tajima, H., Kawarabayasi, Y.
    Identification of an extremely thermostable enzyme with dual sugar-1-phosphate nucleotidylyltransferase activities from an acidothermophilic archaeon, Sulfolobus tokodaii strain 7.
    J. Biol. Chem. 280 : 9698-9705 (2005). [PMID: 15598657]
  2. Zhang, Z., Akutsu, J., Kawarabayasi, Y.
    Identification of novel acetyltransferase activity on the thermostable protein ST0452 from Sulfolobus tokodaii strain 7.
    J. Bacteriol. 192 : 3287-3293 (2010). [PMID: 20400541]
  3. Dadashipour, M., Iwamoto, M., Hossain, M.M., Akutsu, J.I., Zhang, Z. and Kawarabayasi, Y.
    Identification of a direct biosynthetic pathway for UDP-N-acetylgalactosamine from glucosamine-6-phosphate in thermophilic crenarchaeon Sulfolobus tokodaii.
    J. Bacteriol. 200 (2018). [PMID: 29507091]

[EC created 2018]