EC - Lyso-ornithine lipid O-acyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
lyso-ornithine lipid O-acyltransferase
Other name:
olsA (gene name)
Systematic name:
Nα-[(3R)-hydroxy-acyl]-L-ornithine O-acyltransferase



This bacterial enzyme catalyses the second step in the formation of ornithine lipids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Weissenmayer, B., Gao, J. L., Lopez-Lara, I. M., Geiger, O.
    Identification of a gene required for the biosynthesis of ornithine-derived lipids.
    Mol. Microbiol. 45 : 721-733 (2002). [PMID: 12139618]
  2. Aygun-Sunar, S., Bilaloglu, R., Goldfine, H., Daldal, F.
    Rhodobacter capsulatus OlsA is a bifunctional enzyme active in both ornithine lipid and phosphatidic acid biosynthesis.
    J. Bacteriol. 189 : 8564-8574 (2007). [PMID: 17921310]
  3. Lewenza, S., Falsafi, R., Bains, M., Rohs, P., Stupak, J., Sprott, G. D., Hancock, R. E.
    The olsA gene mediates the synthesis of an ornithine lipid in Pseudomonas aeruginosa during growth under phosphate-limiting conditions, but is not involved in antimicrobial peptide susceptibility.
    FEMS Microbiol. Lett. 320 : 95-102 (2011). [PMID: 21535098]

[EC created 2018]