EC 2.3.1.236 - 5-methylnaphthoic acid synthase

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IntEnz Enzyme Nomenclature
EC 2.3.1.236

Names

Accepted name:
5-methylnaphthoic acid synthase
Other name:
AziB
Systematic name:
malonyl-CoA:acetyl-CoA malonyltransferase (5-methyl-1-naphthoate forming)

Reaction

Comments:

A multi-domain polyketide synthase involved in the synthesis of azinomycin B in the bacterium Streptomyces griseofuscus.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Zhao, Q., He, Q., Ding, W., Tang, M., Kang, Q., Yu, Y., Deng, W., Zhang, Q., Fang, J., Tang, G., Liu, W.
    Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis.
    Chem. Biol. 15 : 693-705 (2008). [PMID: 18635006]

[EC 2.3.1.236 created 2014]