EC - 2,4,6-trihydroxybenzophenone synthase

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IntEnz Enzyme Nomenclature


Accepted name:
2,4,6-trihydroxybenzophenone synthase
Other names:
benzophenone synthase [ambiguous]
BPS [ambiguous]
Systematic name:
malonyl-CoA:benzoyl-CoA malonyltransferase (2,4,6-trihydroxybenzophenone-forming)



Involved in the biosynthesis of plant xanthones. The enzyme from the plant Hypericum androsaemum L can use 3-hydroxybenzoyl-CoA instead of benzoyl-CoA, but with lower activity (cf. EC, 2,3',4,6-tetrahydroxybenzophenone synthase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102735


  1. Schmidt, W., Beerhues, L.
    Alternative pathways of xanthone biosynthesis in cell cultures of Hypericum androsaemum L.
    FEBS Lett. 420: 143-146 (1997). [PMID: 9459298]
  2. Nualkaew, N., Morita, H., Shimokawa, Y., Kinjo, K., Kushiro, T., De-Eknamkul, W., Ebizuka, Y., Abe, I.
    Benzophenone synthase from Garcinia mangostana L. pericarps.
    Phytochemistry 77: 60-69 (2012). [PMID: 22390826]

[EC created 2013]